The AIDS Reader: AIDS and HIV News and Information

Ten Clinical Trials That Really Matter

Top 10 trials that were "game changers."

(Image courtesy Wikipedia.)

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This AIDS-specialist offers his rank-order list of the top 10 HIV clinical trials that really made a difference. The trials differ substantially in design, size, and focus, but they all were “game changers.”

If full restoration of immunologic and clinical health is the goal of antiretroviral therapy, the best chance we have is to start ART within 12 months of infection.

Increasing clinical evidence suggests that statins may help prevent cancer in certain HIV-1 infected patients. Details here.

Does the HIV epidemic represent primarily a failure of the public health system--or is it more likely a result of failure on an individual level to take steps necessary to prevent infection?

"Don't ask, don't tell" seems to apply to gay and bisexual men when it comes to discussions about HIV with their physician. Worrisome details from a new Kaiser Family Foundation survey here.

There is emergent need to improve recognition and management of COPD in HIV-infected patients. Details here.

Despite gains, the sobering reality is that HIV transmission-- primarily via sexual means--continues at an unacceptably high rate in the United States.

  • Sandra McCoy PhD

    (AUDIO) Now that HIV testing is universally mandated, what are the best ways to reach into a community to find those who remain untested? In this brief recorded interview, the head of a study designed to test two approaches describes why either one is better than the status quo.

  • (AUDIO) In a brief podcast, the director of the University of North Carolina infectious diseases center ponders the implications of new HIV strains that lead to AIDS symptoms significantly faster than in the past. To him, the response is obvious. What troubles him is that not everyone seems to sense the urgency

  • (AUDIO) The past year has been revolutionary for HIV-positive patients, both in medical care and in policy. And more is in store for the coming year, according to Dr. Michael Horberg of Kaiser Permanente. Listen as the immediate past president of the HIV Medicine Association briefly reviews events of 2013 and forecasts 2014.

  • (AUDIO) Now that guidelines mandate testing all adults for HIV status, what are the best ways to convey the results of this important but often sensitive test? Listen as the co-director of Emory University's Center for AIDS Research offers insights for effective communication on this topic.

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