Drug-resistant HIV strains that pass from mother to infant can go undetected in the baby’s immune system cells and remain there for years, according to a study by Deborah Persaud, MD, of Johns Hopkins University School of Medicine and colleagues (Reuters. April 30, 2007).
Much has been written over the years about the prevalence of HIV drug resistance mutations and about the fitness and transmissibility of resistant strains of virus and their present and potential impact on the HIV pandemic.
A49-year-old woman was referred to the emergency department by her primary medical provider for complaints of 3 weeks of cough, pleuritic chest pain, fever, and night sweats. The patient reported
anorexia and weight loss of 9 kg (20 lb) during the past 4 months.
Scientific discoveries typically begin with basic laboratory research followed by transition to clinical care of the patient.
HIV/AIDS-related pain remains a clinically challenging condition despite recent advances in treatment modalities. The existing data on pain in HIV-positive persons demonstrate a high prevalence, wide variability in clinical presentation, significant negative impact on health-related quality of life, and alarmingly inadequate assessment and management.
Fetal megavesica is a rare syndrome caused by morphological or functional obstruction of the fetal urethra. It is the textbook example of a single cause producing a sequence of changes in fetal development.