Answer: B. Anal cancer
According to the 2018 NCCN guidelines, the following are AIDS-defining malignancies: cervical cancer, Kaposi sarcoma, and aggressive non-Hodgkin lymphoma. The following are non–AIDS-defining malignancies: anal cancer, non–small cell lung cancer, Hodgkin lymphoma, and other non–AIDS-defining malignancies such as prostate cancer, liver cancer, colorectal cancer, oral/pharyngeal cancer, and breast cancer.1
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1. Reid E, Suneja G, Ambinder RF, et al. Cancer in People Living With HIV, Version 1.2018, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2018;16:986-1017. doi: 10.6004/jnccn.2018.0066.
2. Robbins HA, Pfeiffer RM, Shiels MS, et al. Excess cancers among HIV-infected people in the United States. J Natl Cancer Inst. 2015;107(4). pii: dju503. doi: 10.1093/jnci/dju503. Print 2015 Apr