• Largest cohort study of sex differences in HIV-related cognitive impairment found HIV-positive women had 2.5 higher odds of impaired attention and 5 times higher odds of impaired psychomotor speed compared with HIV-positive men.
• HIV-positive women also showed significant impairments in executive function and cognition related to daily tasks compared with HIV-positive men.
• Ongoing studies plan to evaluate biological differences and age-related changes that may differentially affect cognition in HIV-positive women vs HIV-positive men.
1. Maki PM, Rubin LH, Springer G, et al. Differences in cognitive function between women and men with HIV. J Acquir Immune Defic Syndr. 2018 May 25. doi: 10.1097/QAI.0000000000001764.