May 10th 2024
While Moderna expects mRNA-1345 to be approved later this month, the company cites FDA administrative constraints as reason for delay.
April 30th 2024
Your daily dose of the clinical news you may have missed.
April 22nd 2024
Researchers found that the COVID-19 booster dose elicited a 71%-84% increase in the median anti-spike half-life over that of the primary series.
March 29th 2024
Investigators found vaccine uptake of 41% among unvaccinated individuals who were part of a messaging intervention in the emergency department.
March 19th 2024
The novel 21-valent pneumococcal vaccine remains on track for the FDA PDUFA date of June 17, 2024; Merck adds this new data to the body of positive evidence.
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of September 15, 2022
Data from the CDC on US vaccination and booster shot rates and from the Johns Hopkins COVID-19 interactive map on cases and deaths in the US and worldwide.
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of September 13, 2022
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of September 12, 2022
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of September 9, 2022
COVID-19 Bivalent Booster Shot Q&A for Clinicians
Get answers to 7 questions you may have regarding bivalent booster dose vaccination for patients from the US Centers for Disease Control and Prevention.
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of September 8, 2022
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of September 7, 2022
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of September 6, 2022
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of September 2, 2022
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of August 31, 2022
FDA Authorizes Pfizer and Moderna Updated COVID-19 Booster Shots
The FDA EUA amendments for updated booster vaccinations are based on clinical studies of the omicron BA.1 variant and preclinical data on the BA.4 and BA.5 variants.
The Future of US Antimicrobial Resistance is in Our Hands and There is Work to Do
Steer clear of antibiotic Rxs whenever possible, says Anne Meneghetti, MD, to help the US get back to pre-COVID levels of antimicrobial stewardship.
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of August 30, 2022
Primary Care Can Help Restore US Antibiotic Stewardship, Starting with Flu Shots
Preventing viral infections with vaccination can keep the most vulnerable out of the hospital, reducing the risk of bacterial superinfections.
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of August 29, 2022
Superinfection Rate in Hospitalized COVID-19 Patients was Found to be Low
Only 9% of inpatients with COVID-19 had a bacterial superinfection that could be treated with antibiotics which curbed use of broad-spectrum antimicrobials.
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of August 26, 2022
Antimicrobial Resistance During COVID-19 Gained New Ground: Expert Perspective
Widespread antibiotic prescribing in the first year of the pandemic set back US progress on the fight against antimicrobial resistance, says Anne Meneghetti, MD.
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of August 25, 2022
Three Flu Season Imperatives: Vaccinate the Young, the Old, and Everyone in Between
Influenza season in the southern hemisphere is "substantial," says Dr William Schaffner. To prepare: "Vaccinate, vaccinate, vaccinate!"
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of August 24, 2022
COVID-19, Flu, or Both—There are Always Patients on the Fence
The patients on the vaccine fence are the ones that take the extra time and, over time, an added measure of patience for the clinician.
Moderna Requests Emergency Use Authorization for COVID-19 Bivalent Vaccine
Moderna filed with the FDA for emergency use authorization of a 50-µg dose of a BA.4./BA.5 Omicron-targeting bivalent booster vaccine for those aged ≥18 years.
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of August 23, 2022
Pfizer-BioNTech Request EUA for Bivalent COVID-19 Vaccine for Fall
Pfizer-BioNTech filed with the FDA for emergency use authorization of a 30-mcg dose of an Omicron BA.4.BA.5-adapted vaccine for those aged ≥12 years.
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of August 22, 2022
HHS: Monkeypox Vaccine Production to Begin in the US as Cases Surpass 14 000
Federal officials have announced an agreement between Jynneos manufacturer Bavarian Nordic and a Michigan-based drug maker to "fill and finish" US-owned doses.
COVID-19 Update: US Vaccinations, Booster Doses, & Global Data as of August 19, 2022
William Schaffner, MD: "If It's Not Flu and It's Not COVID, It's Probably RSV"
Respiratory virus season is top of mind for Schaffner, medical director of the National Foundation for Infectious Diseases, and he says it's going to be a challenge.
COVID-19 Vaccine Risk Presented in Context Could Improve Uptake
Pair the risk of side effects associated with a COVID-19 shot with the risk of death in a car accident and see what happens. It worked in this study.