May 10th 2024
While Moderna expects mRNA-1345 to be approved later this month, the company cites FDA administrative constraints as reason for delay.
May 9th 2024
A new analysis found triple therapy for COPD, particularly B/G/F, more cost-effective vs dual therapy in terms of exacerbations and quality-adjusted life years.
May 8th 2024
The company will present new data on effects of tezepelumab in COPD and of inhaled triple therapy Breztri on cardiopulmonary outcomes in COPD.
Your daily dose of the clinical news you may have missed.
May 2nd 2024
Nearly 20% of an older cohort with COPD reported anxiety that was subsequently associated with more severe symptoms and acute exacerbations.
Managing EVALI Patients during Flu Season: 6 CDC Recommendations
These 6 recommendations from the CDC can aid physicians in differential diagnosis and treatment of EVALI and the flu.
Vaping-Related Lung Injury: New CDC Recommendations for Primary Care Physicians
The multistate outbreak of vaping-related lung injury is ongoing, but the CDC's updated interim guidance can help physicians navigate the clinical evaluation and management of these patients.
Vaping-Related Lung Injury in the US: A Pop Quiz
How current are you on the outbreak of lung injuries associated with e-cigarette use, as of today? Take our pop quiz on the latest facts and figures to find out.
Lung Injury Associated with E-Cigarette Use: An Update
Get highlights from a new CDC report with the most recent number of reported cases, patterns of the outbreak, patient characteristics, and more.
ED Use in COPD Linked to Depression, Loneliness
Findings: COPD patients who are lonely and depressed are at increased risk for ED use and hospital admission. Even mild depression is a risk factor.
COPD Insights for Primary Care: 5 New Studies
Findings: Don’t blame patients for all inhaler-use errors; singing may help improve breathing, QOL; Rx adherence does improve over time; plus 3 more outcomes of interest.
Components and Health Consequences of Electronic Cigarettes
A pulmonologist summarizes key research and guidance on the harmful effects of e-cigarettes.
Cystic Fibrosis Guideline Update: 7 Questions
Cystic fibrosis treatment guidelines must evolve to keep pace with new treatments and disease knowledge. Try 7 questions on the latest iteration.
New CF Adherence Intervention Starts Strong
Pilot study success with a new cystic fibrosis treatment adherence tool may augur similar positive results from current RCT. Outcomes are due, soon.
Vaping-related Respiratory Disease Requires Intubation for Some
Recent vaping behavior is the only commonality found among teens and young adults hospitalized in 2 midwestern states, for severe respiratory symptoms.
ATS Highlights Advances in the Prediction of COPD Outcomes
DALLAS--Results of 3 studies presented at the American Thoracic Society meeting this week focus on the predictive role of disease exacerbations, machine learning, and Hgb levels in COPD.
E-Cigarettes: The New Addiction and Why Physicians Must be Concerned
DALLAS-At the American Thoracic Society meeting thought leaders cited disturbing trends in e-cigarette use by teens and warned of health dangers, known and unknown.
Choking and Chest Tightness: Asthma or Something Else?
A 37-year-old man recently was diagnosed with asthma and prescribed a dry-powder inhaler. He says it's not working and actually making his symptoms worse. What's wrong?
3 Things Your COPD Patients May Not Tell You
"I'm having trouble catching my breath." "I can't pay for my inhaler." "I'm just so sad." They may not tell us, so we need to ask. Here's my experience.
Why Physicians Fire Patients: My Informal Survey
Only 1 respondent to this physician’s poll had never discharged a patient. Those who had cited abusive behavior, dangerous noncompliance, intuition, and more.
Older Man with Cough and Shortness of Breath: A Surprising Diagnosis
Simultaneous events can confuse a clinical picture. In this case, the ECG offers clues to an event that occurred during an episode of bronchitis.
Progressive Dyspnea & Chronic Cough: One Disease or Two?
Beth is age 52, smokes 2 packs of cigarettes a day, gets breathless in cold weather, and has had "bronchitis" twice this year. What's your diagnosis?
Mild Asthma, Poorly Controlled: A Case In Point
"Cindy" says she's using her albuterol inhaler up to 6 times a day, but her asthma is worse. A pulmonologist poses 4 questions that can lead to preferred Rx.
Idiopathic Pulmonary Fibrosis: How to Recognize and When to Refer
This compact yet detailed slide show offers primary care physicians a guide to essentials of IPF diagnosis and when to refer for pulmonary consult.
A Non-smoker with Progressive Dyspnea, No Cough
Dorothy is 55-years-old, has never smoked, and was well until 1 year ago when she first noticed mild dyspnea on exertion; it has gotten progressively worse.
COPD Exacerbations: Frequently Asked Questions
A pulmonologist answers some of the most common questions he hears from colleagues and students about COPD exacerbations and their management.
An Introduction to Idiopathic Pulmonary Fibrosis
What are the early warning signs and symptoms of IPF? Click through this concise overview of the disease and its differential diagnosis.
A Primary Care Approach to Interstitial Lung Disease
A pulmonologist describes an approach to guide the primary care clinician faced with a patient in whom interstitial lung disease is suspected.
A Case of Worsening Dyspnea and Cough
Montelukast Adds Little For Elderly Asthma Patients
A new study’s lead author notes, however, that lack of significant effect may have been secondary to important study limitations.
Childhood Respiratory Tract Infections Linked to Later Asthma
Lower respiratory infections in children seem to predispose to poor adult lung function, but causation and directionality have yet to be determined.
Hidden Respiratory Dangers at Home
Household bleach may not lead to COPD, as recently reported in the lay press, but a number of respiratory dangers are present in many US homes.
Previous Asthma Exacerbations Predict Future Events in Mild, Moderate Disease
Study authors propose a new asthma patient “phenotype” in which a previous severe event is the sole predictor of another one.
Lipid Levels Linked to Inflammation in Atopic Asthma
Results of a recent study into the role of lipids in atopic asthma could help identify new targets for therapy.
More Doubt Cast on CPAP for Reducing CVD Risk in Sleep Apnea Patients
Some find new meta-analysis results disturbing; others say they underscore the need for more focused research.